Illustrations

Figure 1.  Nomenclature

MGMM = maternal grandmother’s mother; MGMF = maternal grandmother’s father. MGFM = maternal grandfather’s mother; MGFF = maternal grandfather’s father. PGMM = paternal grandmother’s mother; PGMF = paternal grandmother’s father. PGFM = paternal grandfather’s mother; PGFF = paternal grandfather’s father; MGM = maternal grandmother; MGF = maternal grandfather; PGM = paternal grandmother; PGF = paternal grandfather; M = mother; F = father.

Table: Summary of sex specific differences concerning the associations between grandmother smoking during pregnancy and adjusted outcomes to the grandchild (adapted from Golding et al 2021)

Grandmother Grandchild outcome Grandson Granddaughter
       
Maternal (MGM) Fetal growth Greater
  Lean mass Greater
  Strength and fitness Greater
  Autistic traits Increased
  Myopia by 7 Greatly reduced Reduced
  Sensitivity to noise More sensitive Less sensitive
 
Paternal (PGM) Height Taller
  Fat mass Increased
  Verbal IQ Reduced
  Persistent wheeze Greater
  Diagnosed asthma Greater
  Extreme taster Greater
  Religious belief Reduced